Drug Resistance and Genotyping

Transmission of drug-resistant virus strains is well documented and associated with suboptimal virologic response to initial antiretroviral therapy (ART). The risk of acquiring drug-resistant virus is related to the prevalence of drug resistance in infected persons engaging in high-risk behaviors in a given community. Similarly drug resistance in Mycobacterium tuberculosis is growing concern in developing countries, hence information on drug resistance mutation is key in successful treatment.