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The Value of A2 Milk Testing

July 12, 2025by Gauri Lambhate0
Meet Kavita—and Her Quest for “Good” Milk

Kavita is a busy mom in Pune who starts every morning with a glass of warm milk for her two children. When her younger son often complained of tummy aches afterward, she wondered whether “A2 milk”—a term she kept seeing on shop labels—could really make a difference. But how could she be sure the claims on each bottle were true?

Her search led her to A1/A2 genotyping, a simple DNA test that reveals which beta-casein protein a cow produces. And that test, in turn, brought her to GeneOmbio Technologies—the first NABL- and ISO/IEC 17025-accredited lab in the region to offer gold-standard Sanger sequencing for the CSN2 gene.

Why the “A” Matters: A1 vs A2 Beta-Casein
  • Beta-casein is one of the major proteins in cow’s milk.
  • A single DNA “letter” change in the CSN2 gene swaps the amino acid at position 67: histidine in A1 milk, proline in A2 milk.
  • Some studies suggest A1 milk releases a peptide (BCM-7) during digestion that may cause discomfort for sensitive people, while A2 milk appears gentler on many stomachs.

For consumers like Kavita, the difference can mean fewer digestive upsets—and greater confidence in every sip.

How Genotyping Protects Everyone in the Dairy Chain

For Families For Dairy Farmers For Brands & Retailers
Verify “A2” labels before buying Select & breed A2-only animals Differentiate products in a crowded market
Reduce trial-and-error diet changes Command a premium price for certified A2 milk Build trust with lab-verified claims
Support children and elders with sensitive digestion Plan herd genetics with long-term clarity Avoid regulatory penalties for mislabeling

The Science Behind the testing

  1. Sample Collection– Raw milk, or tiny bit of hair, blood, or ear-punch from each cow is enough.
  2. PCR Amplification– We copy only the part of the CSN2 gene that matters.
  3. Sanger Sequencing– The gold-standard technique that reads every DNA letter with near-perfect accuracy.
  4. Clear Results– Each animal is labelled A1A1, A1A2, or A2A2—no guesswork.

Because Sanger sequencing can detect even a single DNA change, farmers and consumers alike can trust the outcome.

Kavita’s Outcome—and Yours

Armed with her new knowledge, Kavita asked her local milk supplier for a geneOmbio certificate. The report showed the herd was A2A2. Word spread in her apartment complex, and soon the same supplier saw demand rise—proof that transparent testing rewards honest producers.

Why Choose GeneOmbio for Your A1/A2 Test?

  • Accredited Accuracy– NABL & ISO/IEC 17025 laboratory standards.
  • Expert Guidance– Friendly scientists who translate genetics into plain language.
  • Fast Turnaround– Results in 5–6 working days, ready for both bulk herds and single-cow owners.
  • Full Confidentiality– Your data and your herd’s value stay protected.

Ready to Test?

Whether you’re a parent seeking peace of mind or a dairy brand aiming to lead the A2 revolution, geneOmbio makes the process effortless.

Call us at +91-9766363481 or email to vetgene@geneombiotechnologies.com to book your test today.
Discover how one tiny gene can make a world of difference to the milk in your glass.

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